Supplement — editorial review

Glucosamine

Editorial page for the supplement Glucosamine.

Low evidenceEditorial draft
Type
Supplement
Reviewed by
Last reviewed
2025-09
Next review
2026-09

This page is part of the Osteoarthritis Observatory and covers glucosamine.

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Magnitude

Small to moderate effect size in some subgroups; not consistent across trials.

Safety

Generally favourable short-term profile; specific interactions pending review.

InteractionsPossible interactions with anticoagulants and other chronic treatments.

Regulation

Food supplement: not equivalent to an authorised medicinal product.

Limitations

Methodological heterogeneity and documented publication bias.

FundingSome trials have been industry-funded; consider conflicts of interest.

Editorial conclusion

Does not replace interventions with stronger evidence (exercise, weight control).