Supplement — editorial review
MSM
Editorial page for the supplement MSM.
- Type
- Supplement
- Reviewed by
- —
- Last reviewed
- 2025-09
- Next review
- 2026-09
This page is part of the Osteoarthritis Observatory and covers msm.
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Magnitude
Small to moderate effect size in some subgroups; not consistent across trials.
Safety
Generally favourable short-term profile; specific interactions pending review.
InteractionsPossible interactions with anticoagulants and other chronic treatments.
Regulation
Food supplement: not equivalent to an authorised medicinal product.
Limitations
Methodological heterogeneity and documented publication bias.
FundingSome trials have been industry-funded; consider conflicts of interest.
Editorial conclusion
Does not replace interventions with stronger evidence (exercise, weight control).